A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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‘Indeed, that may be about proper. I try to find a physical comprehension of Organic techniques inside of a bottom-up way. I do think you may distinguish a few strains of analysis in my team for the time being. The 1st concerns chromosome construction: How will you receive a metre-long DNA polymer folded and organised in this type of microscopic mobile? We have created visualisation tactics that allow for us to study how, as an example, SMC proteins loop DNA (movie on Youtube) so as to build up chromosomes.
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Across the same time, the team of Paul McEuen, who was then primarily based within the College of California, Berkeley, showed similar success on ropes of bundled nanotubes. Dependant upon the wrapping angle, nanotubes can are available in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard University independently verified employing scanning tunnelling spectroscopy experiments.
Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on one molecules and metal clusters
2015, discovery that condensin is often a really adaptable protein construction; and first detection of DNA knots applying nanopores
The coiled-coil of your human Rad50 DNA mend protein consists of unique segments of enhanced flexibility
Since 2000 he moved to one-molecule biophysics and nanobiology, with exploration from DNA supercoiling reports of nucleosomes and DNA fix proteins to DNA translocation through nanopores. A short while ago his exploration has focused on researching mobile division with germs on chip, though his best curiosity is in the course of acknowledging synthetic cells.
2000, discovery that nanotubes can have extraordinary huge latest densities; resolved the controversial concern of Digital transportation by means of DNA molecules by measurements of insulating actions at the single molecule level; and demonstration of the AFM procedure for single-molecule manipulation of nanotubes
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At this time, we also understood that it ought to be attainable to implement an individual semiconducting carbon nanotube to generate a transistor — and we set out to make it. We stretched individual semiconducting nanotubes throughout metallic electrodes and made use of the fundamental silicon substrate for a gate electrode, developing the basic three-terminal structure of the discipline-impact transistor (Fig.
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Cees Dekker is Distinguished College Professor at TU Delft. Qualified being a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes from the nineteen nineties. Due to the fact 2000, he https://www.ceesdekker.net moved to solitary-molecule biophysics and nanobiology. His recent investigation concentrates on (i) nanopores for protein sequencing; (ii) chromosome construction, particularly SMC motor protein; and (iii) building a living artificial mobile from lifeless molecules. Dekker is undoubtedly an elected member on the KNAW and fellow for the APS along with the IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart design in 2005. (nl)